Treating neurological disorders by complement activation
Complement Pharma aims to develop new therapies for neurological disorders. This development is based on research findings from the lab of Prof. Baas. Prof. Baas and his team found that damaged nerves activate, the complement system, a part of our innate immune system. This activation results in collateral damage to the nervous system and impedes regeneration.
Our immune system's normal reaction is to clean up damaged and dead nerve cells. Activation of the innate immune system plays an important role in this process. However, the formation of MAC (Membrane Attack Complex), the product of the terminal pathway, has detrimental effects.